Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

While traditional Chinese medicine (TCM) is considered a valuable resource for drug discovery and form potential basis development, they also carry substantial safety risks due to adverse reactions lack of understanding their mechanisms action. However, highly complex composition, valid analytical methodologies analyzing TCMs must be developed promoted. An extensive search published research review scientific papers implies that the increased efficiency sensitivity capillary electrophoresis (CE) has attracted much attention. This provides an in-depth assessment CE applications TCM analysis in open literature last decade (2011–2021). Our survey findings showed zone (CZE) with ultraviolet (UV) detection electromigration technique frequently utilized efficient separation, identification, quantitation various active components matrices. Different extraction methods, modifiers background electrolyte, preconcentration techniques, mass spectrometry (MS) detectors are used enhance separation selectivity sensitivity.